There's really no subject more fearful than stage four back cancer. Actually...technically...there is no such disease. This does not stop Kyle (Seth Rogen) from using his friend Adam's recent cancer diagnosis to try to score chicks for them both. Kyle divulges the "back cancer" to a bookstore clerk, playing the sensitive friend to help his friend, "the little guy over there in the cap," purchase self-help books. This wins Kyle a date with the clerk. But before more ill-gotten nookie can be had, the date is interrupted when Kyle sees Adam's girlfriend, Rachael (Bryce Dallas Howard) getting friendly with a another man at a gallery show while his ill friend lays forlornly on his couch waiting for her. As identified by Kyle, Rachael is another Big C in Adam's life. While not exactly a paragon of selfless friendship, Kyle is at least loyal and a rare source of candor. The friend and soon-to-be-ex-girlfriend are just two dubious parts of Ada...